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Varicella-zoster virus Infection (VZV)

Chickenpox/HERPES ZOSTER

Identification 

            The varicella-zoster virus causes two distinct diseases:

In pregnant women

In newborn

Congenital varicella syndrome

Varicella diagnosis in Pregnant woman

 

Diagnosis in newborn (neonatal)

 

Note Bene. In this document, the laboratory diagnosis was not treated in the VZV infection, but there were several elements related to pregnancy and newborn. For the complete diagnosis of this infection, those interested will be addressing infectionists physicians.

The infectious agent

The varicella-zoster (VZV) virus is a double stranded DNA virus, belonging to the Subfamily alpha herpes viruses, the Herpesviredae family. [15]Shrim A et al. Management of varicella infection (chickenpox) in pregnancy. J Obstet Gynaecol Can. 2012; 34(3):287-92*. [16]Biskupska M et al. Varicella—a potential threat to maternal and fetal health. Ginekologia Polska. 2017; 88(1):13-9. [17]Cernescu C., Virusologie medicala, Ed Medicala 2008`~

Incidence and prevalence

 

Source

The man is the only known host. [19]Wang L et al. Efficacy of varicella (VZV) vaccination: an update for the clinician. Ther Adv Vaccines. 2016; 4(1-2):20-31.

 

Method of transmission

 

Risk groups

Incubation period

The incubation period varies between 10-21 days, with an average of 14-16 days, can be extended to 28 days by passive immunization against chickenpox, is shorter at immunosuppressed. [22]Gardella C, Brown ZA. Managing varicella … in pregnancy. Cleve Clin J Med. 2007; 74(4):290-6.`

 

Infectiousness period

 

Prophylaxis

Vaccination

 

Administration of Immunoglobulins against chickenpox (VZIG or VariZIG)

Birth to the woman infected with VZV

Is carried out naturally

 Breastfeeding

There are no contraindications.

Treatment

 Bibliography

  1. Gardella C, Brown ZA. Managing varicella zoster infection in pregnancy. Cleve Clin J Med. 2007; 74 (4): 290-6.
  2. Shrim A, Koren G, Yudin MH, Farine D. Management of varicella infection (chickenpox) in pregnancy. J Obstet Gynaecol Can. 2012; 34 (3): 287-92.
  3. Ramachandra s, Metta AK, Haneef NS, Kodali S. Foetal varicella syndrome. Indian J dermatologisty Venereol Leprol. 2010; 76 (6): 724.
  4. Lamont RF, Sobel JD, Carrington D, Mazaki ‐ Tovi S, Kusanovic JP, Vaisbuch E, Romero R. Varicella ‐ zoster virus (chickenpox) infection in pregnancy. BJOG. 2011; 118 (10): 1155-62.
  5. Sauerbrei A. Preventing congenital varicella syndrome with immunization. CMAJ. 2011; 183 (3): E169-70.
  6. Smith CK, Arvin AM. Varicella in the fetus and newborn. Neonatal foetal semen. 2009 Aug; 14 (4): 209-17.
  7. Sauerbrei A, Wutzler P. Neonatal varicella. J Perinatol. 2001; 21 (8): 545-9.
  8. Biskupska M, Małecka i, Stryczyńska-Kazubska J, Wysocki J. Varicella — a potential threat to maternal and fetal health. Ginekologia Polska. 2017; 88 (1): 13-9.
  9. Wang L, Zhu L, Zhu H. Efficacy of Varicella (VZV) Vaccination: An update for the clinician. Ther ADV Vaccines. 2016; 4 (1-2): 20-31.
  10. European Centre for Disease Prevention and Control. Varicella vaccination in the European Union. Stockholm: ECDC; 2015.
  11. Sur DK, Wallis DH, O’Connell TX. Vaccinations in pregnancy. I got the Physician. 2003; 68 (2): 299-304.
  12. Cernescu C., Medical Virology, Ed Medicala 2008
  13. CDC. Heymann D.L., management Manual of communicable diseases. 2012

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