Syphilis is more common in people aged 20 to 45 years.This pathology is spread globally, with 10.6 million new cases of syphilis reported in 2008. About 1 million children are born annually with congenital syphilis. After the appearance of penicillin, the incidence of syphilis was decreasing until 2000, but in the last years a steady increase is observed.

Recent studies published in 2015 by CDC (Centre of Disease Control), Disease Control Centre, Atlanta, GA, United States, confirms in a large report that after a long period of decline, in the period 2012-2014 the incidence of congenital syphilis increased at alarming odds, higher odds even than 15 years ago (copies the incidence of syphilis in the adult). The growth has been observed in all races, ethnicities and religions.

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