With regard to disease control, several measures should be taken, including the correct treatment of all the diagnosed cases and in the same time monitoring and treating sources of infection and their contacts. Other measures include sexual hygiene and prophylaxis at the time of exposure, both condom and penicillin.

Treatment is performed with penicillin, but in some cases ceftriaxone, tetracycline or doxycycline may be administered (in case of hypersensitivity to penicillin).

All children born from seroreactive mothers should be treated with penicillin.

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